Senior Bioinformatician, Quantitative Biology

Are you a quantitatively-minded scientist looking to apply bioinformatics and statistical modelling to address biological questions for drug discovery? Would you like an exciting new challenge in a company that follows the science and turn ideas into life changing medicines? Then why not join our Quantitative Biology team in Gothenburg, Sweden or Cambridge, UK!

We are now recruiting a Senior Bioinformatician, Quantitative Biology to join the Discovery Science organization in either Gothenburg, Sweden or Cambridge, UK.

Discovery Science is part of Innovative Medicines and Early Development (IMED), AstraZeneca's small molecule biotech units that deliver candidate drugs into late-stage clinical development. Discovery Science functions across the therapeutic areas to support projects in the drug discovery pipeline from target discovery all the way to clinical candidates. The Quantitative Biology team is a multi-disciplinary team of data scientists with the purpose of providing quantitative insights to biology. We do so by improving the biological understanding of the target and its engagement, including supporting the identification of molecular mechanisms of action, providing image and data analysis solutions to high dimensional datasets, and by enhancing AstraZeneca's ability to prioritize target selection and portfolio projects based on probability of technical success.

Main Duties and Responsibilities

As a Senior Bioinformatician your main responsibilities will involve:

* Using bioinformatics and statistical modelling you will collaborate with drug discovery projects and therapeutic areas to identify and deliver solutions for addressing key biological questions
* Developing or internalizing appropriate algorithms, techniques and datasets to answer defined biological questions
* Building knowledge of and creating data analysis capabilities, typically on complex, high-dimensional -omics data across the research and development organization
* Contributing to and leading local and global projects for NGS, proteomics, and CRISPR
* Ensuring that results are scientifically robust and documented
*

Essential Requirements

* PhD, or equivalent, in bioinformatics, mathematics, computer science, statistics, engineering or the life sciences
* Expertise in one or more of the core competency areas: network biology, multivariate and/or high dimensional data analysis (-omics), knowledge engineering, ontologies, data management, text mining, NLP, machine learning, statistical modelling, multivariate data analysis, classification/regression
* Experience with relevant software tools such as R, Python, Shiny, Spotfire, Java, C/C++, SQL/NoSQL/RDF, JavaScript
* Basic understanding of molecular biology, cell biology, and human physiology
* Excellent English, spoken and in writing

If you are interested, apply now!

For more information about the position please contact: Lars Carlsson at +46 31 7762946 or Ian Barrett +44 7469 400500.

Welcome with your application no later than January 31, 2018

AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.